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An integrated approach of multiple 'omics' techniques for the detection of ecologically relevant biomarkers for Daphnia magna.

Daphnia magna, a frequently used standard organism in laboratory toxicity testing was chosen for this study. In laboratory toxicity testing it is often assumed that organisms will respond in a similar manor as in a field situation. However, in realistic environments multiple factors and stressors, such as the differences in temperature, food availability, etc.... may strongly interfere with responses to pollutant stress. Moreover, organisms are almost always exposed to mixtures of chemical stressors in natural situations. From a toxicological point of view, these interactions can highly influence the overall impact of chemical stressors.

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