The fundamental aim of this project is to develop and to validate a mathematical model to transform concentrations of the most prescribed and used pharmaceuticals and their metabolites of which the us
Pharmaceuticals
Toxicity identification and evaluation of neuro-active chemicals in zebrafish
During the production and after therapeutic use pharmaceutical compounds can enter the aquatic environment through industrial and household discharges. Indeed, pharmaceuticals are continually released into the environment wherever humans live. But until recently, very little attention has been paid on what happens to these these compounds after their administration or use. Human pharmaceuticals have ‘enjoyed’ several decades of unrestricted discharge to the environment. Over the last decade, the increasing number of reports on the occurrence of human pharmaceuticals in the aquatic environment has raised public concern on the environmental risk of these compounds. The big unknown however, is whether the presence of low concentrations of human pharmaceuticals in the aquatic environment can cause a serious threat. Currently, very little is known on the potential adverse effects of human pharmaceuticals on aquatic organisms, and there is a great need for relevant and specific ecotoxicological effect data in order to correctly assess the environmental risk of pharmaceutical compounds.
