Zebrafish

Thyroid hormones (THs) are known to be essential for growth and development related processes in vertebrates in general and especially in early life stages.

This research addresses some key consequences, effects and differences of the short-term and long-term uptake and accumulation of an essential (Zn) and a non-essential (Cd) metal in the fresh water fi

Peroxisome proliferator activated receptor (PPARs) are members of the of the nuclear hormone receptor superfamily and are implicated in a variety of fundamental biological processes such as lipid metablism, inflammation and cell differentiation. PPARs are ligand mediated transcription factors that can be activated by a group of structurally diverse man-made chemicals, the so called peroxisome prolferators (PPs). This class of PPAR ligands consists of - apart from natural and synthetic fatty acids - a vast amount of human pharmaceuticals (e.g. fibrates) and perfluoralkyl compounds (e.g. PFOS and PFOA), a “new” class of environmental pollutents of which only recently the importance and worldwide dispersion has been reported.

During recent years ecotoxicology has been an emerging field and its experimental focus has been expanded from using mainly chemical stressors (e.g. cadmium) to assessing the effects of natural or non-chemical stressors (e.g.

We all know that since the beginning of the 20th century, the industry is the driving force behind the introduction of new chemicals.