Perfluorinated organic compounds (PFOCs) are manufactured for over 50 years in enormous quantities and are used in materials such as wetting agents, foam fire extinguishers and stain resistant treatments for leather, paper and clothing. Due to their environmental persistence and tendency to bioaccumulate, the global concern for the potential toxicity of these organic compounds has strongly been rising during the last decade.
Cyprinus carpio
Characterisation and dynamics of metal toxicity in carp by means of gene expression profiling
Although cadmium toxicity is a well studied theme in the field of aquatic toxicology, still little is known concerning the molecular mechanisms of its toxic action. Moreover most laboratory studies only consider waterborne cadmium exposure, whereas dietary exposure can also contribute to the accumulation and effects of cadmium in fish. For a better understanding of the toxic responses leading to adverse effects there is an increasing need for more sensitive tools to determine early reactions on cadmium exposure and accumulation.
