Karlijn van der Ven

History

Member for

3 years 47 weeks

Professional information

Own research projects

• Toxicity identification and evaluation of neuro-active chemicals in zebrafish
• Characterization of peroxisome proliferator activated receptor (PPAR) pathways in the zebrafish (Danio rerio)

Participation in other projects

• Development of a biodiversity chip for the biomonitoring of benthic macro invertebrate communities.
• Characterization of toxicological effects on the energy metabolism after exposure to endocrine disrupting compounds

Position in the lab

Post-doc fellow

Curriculum Vitae

After graduating in Biology (Physiology) at the University of Antwerp (UA) in 2000, I started my professional career at the laboratory for Ecophysiology, Biochemistry and Toxicology research group as a PhD student in October 2000. This research focusses on the investigation of the effects of neuro-endocrine pharmaceuticals in zebrafish (Danio rerio), using a toxicogenomics approach. The first year of my research was funded by the IWT, after which I recieved a 4 year grand of the FWO-Flanders.

In my spare time, I like doing sports. My favorites are sailing, wintersports and swimming. I love animals. Ideal to pass time for me is to go for walks with my dog (although, with his respectable age of 11 years he is getting a bit too old for the ‘real work’). I also like reading and art, and I even ‘try’ to draw and paint myself from time to time.

Selected publications

van der Ven K., Van Dongen W., Maes B., Esmans E., De Coen W. and Blust R. (2003). Determination of Diazepam in aquatic samples by capillary liquid chromatography - electrospray tandem mass spectrometry. Chemosphere 57 (8), 967-973.

van der Ven K., De Wit M., Keil D., Moens L., Van Leemput K., Naudts B., De Coen W. (2005). Development and application of a brain-specific cDNA microarray for effect evaluation of neuro-active pharmaceuticals in zebrafish (Danio rerio). Comparative Biochemistry and Physiology PartB 141, 408-417.

van der Ven K., De Coen W., Robben J. (2003). DNA microarrays – Now in the lab, tomorrow in the clinic. European Journal of Hospital Pharmacy 9 (6): 28-29.

van der Ven K., Keil D., De Wit M., Moens L., Van Leemput K., van Remortel P., De Coen W. (2006). Neuropharmaceuticals in the environment: Mianserin induced neuro-endocrine disruption in zebrafish using cDNA microarrays. Environmental toxicology and Chemistry (Accepted).

van der Ven K., Dorien Keil, Lotte N. Moens, Paul Van Hummelen, Piet van Remortel, Marleen Maras, Wim De Coen. (2006). Effects of the antidepressant mianserin in zebrafish: molecular markers of endocrine disruption. Chemosphere (Accepted).

Selected presentations

van der Ven K., Keil D., De Wit M., Moens L.N., Soetaert A., Van Leemput K., Naudts B., Blust R., De Coen W.M. (2005). Toxicogenomic analysis of zebrafish brain as a potential new tool for effect evaluation of neuropharmaceuticals. SETAC North-America 26th Annuel meeting 13-17 november 2005. Baltimore, MD, USA.

van der Ven K., Keil D., Huyskens G., De Coen W. (2004) Screening of BFR induced differential gene expression in zebrafish Danio rerio: current status and progress. FIRE project midterm meeting. 8-10 december, Texel, Nederland.

van der Ven K., Keil D., Hectors K., De Wit M., Huyskens G., Moens L.N., Okoniewski M, Naudts B., Blust R., De Coens W. (2004). Evaluation of neuro-endocrine disruptive effects in zebrafish using microarray technology. CREDO Cluster workshop on Ecological Relevance of Chemically-Induced Endocrine Disruption in Wildlife. 5-7/7/04, University of Exeter, UK.

van der Ven K., Huyskens G., Moens L. Blust R. and De Coen W. (2003). Pharmaceuticals in the environment: the use of toxicogenomics for effect identification and evaluation. ESCPB 22nd Annual Meeting, 14-18 december, Allessandria, Italy.